Longitudinal study of BMI and Obesity as risk factors for renal graft rejection

Authors

  • Adelina Martín Salvador Universidad de Granada. Facultad de Ciencias de la Salud. Departamento de Enfermería
  • Inmaculada García García Universidad de Granada. Facultad de Ciencias de la Salud. Departamento de Enfermería
  • María José Aguilar Cordero Universidad de Granada. Facultad de Ciencias de la Salud. Departamento de Enfermería
  • Rafael José Esteban de la Rosa Servicio de Nefrología Unidad de Hemodiálisis. Hospital Universitario Virgen de las Nieves. Granada
  • Juan Bravo Soto Servicio de Nefrología Unidad de Hemodiálisis. Hospital Universitario Virgen de las Nieves. Granada
  • Rafael Fernández Castillo Universidad de Granada. Facultad de Ciencias de la Salud. Departamento de Enfermería

DOI:

https://doi.org/10.19230/jonnpr.2189

Keywords:

Kidney transplant, lipid alterations, hyperlipidemia, hypiertriglyceridemia, anthropometry

Abstract

Objective. To evaluate the rejection, the chronic allograft nephropathy (CAN) and the delay in the  function of the same (DGF) due to obesity and high BMI.

Material and method. In this work, 500 patients of both sexes kidney transplant followed for 5 years  were evaluated, post-transplant measurements of biochemical parameters and anthropometric  measurements were made. It was also recognized data of chronic nephropathy and delayed graft function.

Results: Five years after the transplant, there was an increase in BMI and an increase in the components  of the metabolic profile: triglycerides, total cholesterol and hyperglycemia, as well as blood pressure. As a  consequence we have also observed an increase in the incidence of chronic kidney disease and delayed  graft function.

Conclusion. Obesity significantly increases the incidence of post-transplant complications, which can finally  be done through injection. An adequate control of BMI in kidney transplant recipients would directly  influence long-term renal graft survival, which reduced the delay in allograft function, the appearance of  CAN and prolonged renal allograft survival.

 

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Published

2018-01-18