Estudio descriptivo de la utilización del manitol como prueba diagnóstica de hiperreactividad bronquial en Albacete

Raul Godoy Mayoral; Sergio García Castillo; Wanda Almonte Batista; Alfonso García Guerra

doi:10.19230/jonnpr.2914

Authors

Raul Godoy Mayoral Servicio de Neumología del Complejo Hospitalario Universitario de Albacete https://orcid.org/0000-0003-0914-7909
Sergio García Castillo Servicio de Neumología del Complejo Hospitalario Universitario de Albacete
Wanda Almonte Batista Servicio de Neumología del Complejo Hospitalario Universitario de Albacete
Alfonso García Guerra Servicio de Neumología del Complejo Hospitalario Universitario de Albacete

DOI:

https://doi.org/10.19230/jonnpr.2914

Keywords:

Mannitol, bronchial hyperreactivity, asthma

Abstract

The Mannitol test is used for the diagnosis of bronchial hyperreactivity. It is in the asthma diagnostic algorithm

Aims. Make a descriptive review of the tests we had done and their usefulness.

Settings and Design: Retrospective descriptive study.

Methods and Material. Patients who have performed the mannitol test in the laboratory of functional respiratory tests between May 29, 2017 and December 3, 2018.

Statistical analysis used. Study of frequencies in qualitative variables and measures of central tendency in quantitative. The relationships were studied with nonparametric tests: F of Fisher for qualitative variables and U of Mann-Whitney for quantitative variables. The significance was set at p?0.05.

Results. There were 54 patients, 81.5% women of 49.06 years. The most frequent adverse effect was cough that occurred in 85.4% and with a dose of 5 mg. The result was positive at 14.8%. The positives are among those older than 40 years (p = 0.04), so those who cough (p = 0.018). There are significant differences in the dose received and the fall in FEV1. There was no relationship between coughing and the positivity or negativity of the test (p=0.56), nor was there any relationship between gender and cough or positivity.

Conclusions. The mannitol test is a useful test to detect hyperreactivity. The most frequent adverse effect is cough.

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Author Biography

Raul Godoy Mayoral, Servicio de Neumología del Complejo Hospitalario Universitario de Albacete

Facultativo Especialista dxe Neumología. Dr en Medicina Cirugía

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