The aluminum used in wastewater treatment and its possible relationship with Alzheimer's disease

Authors

  • Carlos Alberto Matías-Cervantes Departamento de Ingeniería Química y Bioquímica. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca Unidad de Bioquímica e Inmunología ITO-UNAM. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca
  • Servando López-León Departamento de Ingeniería Química y Bioquímica. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca Unidad de Bioquímica e Inmunología ITO-UNAM. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca
  • Diana Matías-Pérez Unidad de Bioquímica e Inmunología ITO-UNAM. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca
  • Iván Antonio García-Montalvo Departamento de Ingeniería Química y Bioquímica. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca Unidad de Bioquímica e Inmunología ITO-UNAM. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca

DOI:

https://doi.org/10.19230/jonnpr.1704

Keywords:

Aluminum, Alzheimer’s disease, Coagulation

Abstract

Alzheimer's disease (AD) is clinically characterized as a cause of dementia present in older adults. Patients  may experience anxiety and depression. Aluminum (Al) is a common metal in the environment and one of  the most abundant. Most of Al ingestion comes from food, through different forms: food contaminated by  Al, water and industrialized foods that have Al as a preservative and / or coloring, the water being the most  bioavailable form to be absorbed by the intestine. Al is extremely proinflammatory, pathological and genotoxic, which is particularly detrimental to the homeostatic functioning of brain cells, especially at  the level of normal cytoplasmic and genetic activities using phosphate. Its ingestion can lead to gradual loss  of memory. Based on the above, the objective of the  present work is to show systematically revised information from published studies related to the intake of aluminum and Alzheimer's disease.

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Published

2017-11-11