Overdiagnosis: The determination of PSA levels for prostatic cancer, a big Public Health disaster
DOI:
https://doi.org/10.19230/jonnpr.3251Keywords:
Prostate cancer, overdiagnosis, PSA testAbstract
PSA determination, discovered in 1970 by Ablin multiplied by almost 3 the number of prostate cancers
diagnosed in the years that followed. However, this effect was not accompanied by an increase in mortality
secondary to prostate cancer indicating that there was an effect of overdiagnosis, that is, establishment of
prostate cancer diagnoses in circumstances in which it would not progress. For every man who benefits
from screening by avoiding a prostate cancer death, somewhere between thirty and a hundred are harmed
by overdiagnosis and treated needlessly. At present PSA test is not recommended for screening by the
most important scientific cancer and urological organizations. PSA test screening for prostate cancer has
been a major profit-driven public health disaster.
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References
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