Periodontal Disease as a risk factor for complications during pregnancy and childbirth
DOI:
https://doi.org/10.19230/jonnpr.2746Keywords:
Low birth weight, periodontal disease, pregnant womenAbstract
Introduction: Periodontal Disease during pregnancy can influence in maternal-fetal health. Two hypotheses have been established in relation to oral health and alterations in pregnancy. The first one determines that periodontal disease causes immunological changes, which causes complications during pregnancy. The second hypothesis proposes that oral bacteria colonize the placenta, cause inflammatory responses and result in preeclampsia and prematurity.
Objective: To carry out a systematic review on periodontal disease and its relationship with complications during pregnancy.
Methodology: A systematic review was carried out using PRISMA methodology. An electronic search was conducted in three databases (PUDMED, CINAHL and SCOPUS) for articles published in English. The keywords or search terms used were the following: Low birth weight / Low birth weight; Periodontal disease / Periodontal disease, pregnant / Pregnant women.
Results: For this review, 19 specific articles on periodontal disease and its relation to pregnancy complications have been selected.
Discussion / Conclusions: The publications analyzed in this study, according to their results, revealed that the association between periodontal disease and the health of the pregnant women and their baby is still contradictory.
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References
Naciones Unidas, Departamento de Asuntos Económicos y Sociales, División de Población (2017). World Population Prospects: La revisión de 2017, datos personalizados adquiridos a través del sitio web. https://esa.un.org/unpd/wpp/DataQuery/
Liu L, Oza S, Hogan D, Chu Y, Perin J, Zhu J, et al. Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet. 2016; 388(10063):3027-35.
Alkema L, Chou D, Hogan D, Zhang S, Moller AB, Gemmill A, et al. Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Maternal Mortality Estimation Inter-Agency Group. Lancet. 2016; 387(10017):462-74.
Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels JD, et al. Global Causes of Maternal Death: A WHO Systematic Analysis. Lancet Global Health. 2014; 2(6): e323-e333.
Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva https://www.paho.org/clap/index.php?option=com_content&view=article&id=452:22-demayo-dia-mundial-de-la-preeclampsia&Itemid=0&lang=es
INE base/Demografía y población/Fenómenos demográficos/Estadística de nacimientos. Movimiento natural de la población/Últimos datos. (2017). Ine.es.
Niños prematuros: Uno de cada 13 bebés en España. EFE: Salud. https://www.efesalud.com/ninos-prematuros-nacimientos-espana/
Sanz M, Kornman K; working group 3 of the joint EFP/AAP workshop. Periodontitis and adverse pregnancy outcomes: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol. 2013 Apr; 84(4 Suppl):S164-9. Doi: 10.1902/jop.2013.1340016.
Han YW. Oral health and adverse pregnancy outcomes-what's next? J Dent Res. 2011 Mar; 90(3):289-93. Doi: 10.1177/0022034510381905. Epub 2010 Nov 1.
Aguilar-Cordero MJ, Piñero AO, García LB, Segovia JPN, Hernández MCL, López AMS. Efecto rebote de los programas de intervención para reducir el sobrepeso y la obesidad de niños y adolescentes; revisión sistemática. Nutricion Hospitalaria. 2015 Dec 1; 32(n06):2508–17.
Disponible en: http://www.aulamedica.es/gdcr/index.php/nh/article/view/10071
Khan FR, Ahmad T, Hussain R, Bhutta ZA. Relationship among Hypovitaminosis D, Maternal Periodontal Disease, and Low Birth Weight. J Coll Physicians Surg Pak. 2018 Jan; 28(1):36-39. Doi: 10.29271/jcpsp.2018.01.36.
Fogacci MF, Cardoso EOC, Barbirato DDS, de Carvalho DP, Sansone C. No association between periodontitis and preterm low birth weight: a case-control study. Arch Gynecol Obstet. 2018 Jan; 297(1):71-76. Doi: 10.1007/s00404-017-4556-9. Epub 2017 Oct 11.
Meqa K, Dragidella F, Disha M, Sllamniku-Dalipi Z. The Association between Periodontal Disease and Preterm Low Birthweight in Kosovo. Acta Stomatol Croat. 2017 Mar; 51(1):33-40. Doi: 10.15644/asc51/1/4.
Usin MM, Menso J, Rodríguez VI, González A, Tabares S, Parodi R, Sembaj A. Association between maternal periodontitis and preterm and/or low birth weight infants in normal pregnancies. J Matern Fetal Neonatal Med. 2016; 29(1):115-9. Doi: 10.3109/14767058.2014.987751. Epub 2014 Dec 10.
Mesa F, Pozo E, O'Valle F, Puertas A, Magan-Fernandez A, Rosel E, Bravo M. Relationship between periodontal parameters and plasma cytokine profiles in pregnant
woman with preterm birth or low birth weight. Clin Oral Investig. 2016 May; 20(4):669-
Doi: 10.1007/s00784-015-1553-x. Epub 2015 Aug 7.
Pozo E, Mesa F, Ikram MH, Puertas A, Torrecillas-Martínez L, Ortega- Oller I, Magán-Fernández A, Rodríguez-Martínez MD, Padial-Molina M, Sánchez-Fernández E, Galindo-Moreno P, O'Valle F. Preterm birth and/or low birth weight are associated with periodontal disease and the increased placental immunohistochemical expression of inflammatory markers. Histol Histopathol. 2016 Feb; 31(2):231-7. Doi: 10.14670/HH- 11-671. Epub 2015 Sep 29.
Stadelmann PF, Eick S, Salvi GE, Surbek D, Mohr S, Bürgin W, Ramseier CA, Sculean A. Increased periodontal inflammation in women with preterm premature rupture of membranes. Clin Oral Investig. 2015 Jul; 19(6):1537-46. Doi: 10.1007/s00784-014-1371-6. Epub 2014 Nov 26.
Basha S, Shivalinga Swamy H, Noor Mohamed R. Maternal Periodontitis as a Possible Risk Factor for Preterm Birth and Low Birth Weight--A Prospective Study. Oral Health Prev Dent. 2015; 13(6):537- 44. Doi: 10.3290/j.ohpd.a34053.
Penova-Veselinovic B, Keelan JA, Wang CA, Newnham JP, Pennell CE. Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome. J Reprod Immunol. 2015 Nov; 112:1-10. Doi: 10.1016/j.jri.2015.05.002. Epub 2015 May 27. PMID: 26093363
Blanc V, O'Valle F, Pozo E, Puertas A, León R, Mesa F. Oral bacteria in placental tissues: increased molecular detection in pregnant periodontitis patients. Oral Dis. 2015 Oct; 21(7):905-12. Doi: 10.1111/odi.12364. Epub 2015 Sep 7.
Macedo JF , Ribeiro RA , Machado FC , Assis NM , Alves RT , Oliveira AS , Ribeiro LC . La enfermedad periodontal y el comportamiento relacionado con la salud oral como factores asociados con el nacimiento prematuro : un estudio de casos y controles en el sudeste de Brasil. J Periodontal Res. 2014 agosto; 49 (4): 458-64. Doi: 10.1111 /jre.12124. Epub 2013 16 de agosto.
Cassini MA, Pilloni A, Condò SG, Vitali LA, Pasquantonio G, Cerroni L. Bacterias periodontales en el tracto genital : ¿están relacionadas con el resultado adverso del embarazo? Int J Immunopathol Pharmacol. 2013 oct-dic; 26 (4): 931-9. PMID: 24355228. DOI: 10.1177 / 039463201302600411
Mesa F , Pozo E, Blanc V, Puertas A, Bravo M, O'Valle F. Are periodontal bacterial profiles and placental inflammatory infiltrate in pregnancy related to birth outcomes?J Periodontol. 2013 Sep; 84 (9): 1327-36. Doi: 10.1902 / jop.2012.120462. Epub 2012 3 de noviembre.
Haerian-Ardakani A, Eslami Z , Rashidi-Meibodi F, Haerian A, Dallalnejad P , Shekari M, Moein Taghavi A , Akbari S. Relación entre la enfermedad periodontal materna y los bebés con bajo peso al nacer. Iran J Reprod Med. 2013 agosto; 11 (8): 625-30. PMID: 24639799 PMCID: PMC3941365
Santa Cruz I, Herrera D, Martin C , Herrero A , Sanz M . Association between periodontal status and pre-term and/or low-birth weight in Spain: clinical and microbiological parameters. J Periodontal Res. 2013 ago; 48 (4): 443-51. Doi: 10.1111 / jre.12024. Epub 2012 22 de octubre.
Pattanashetti JI, Nagathan VM , Rao SM. Evaluación de la periodontitis como riesgo de parto prematuro entre las mujeres embarazadas preeclámpticas y no preeclámpticas: un estudio de control de casos. J Clin Diagn Res. 2013 Aug; 7 (8): 1776-8. Doi: 10.7860 / JCDR / 2013 / 6497.3308. Epub 2013 1 de agosto.
Chaparro A, Sanz A, Quintero A, Inostroza C, Ramirez V, Carrión F, Figueroa F, Serra R, Illanes SE. El aumento de biomarcadores inflamatorios al inicio del embarazo se asocia con el desarrollo de preeclampsia en pacientes con periodontitis: un estudio de casos y controles. J Periodontal Res. 2013 Jun; 48 (3): 302-7. Doi: 10.1111 / jre.12008. Epub 2012 5 de octubre.
Ercan E, Eratalay K , Deren O , Gur D , Ozyuncu O , Altun B , Kanli C , Ozdemir P, Akincibay H. Evaluación de los patógenos periodontales en el líquido amniótico y el papel de la enfermedad periodontal en el parto prematuro y bajo peso al nacer. Acta Odontol Scand. 2013 mayo-julio; 71 (3-4): 553-9. Doi: 10.3109 / 00016357.2012.697576. Epub 2012 2 de julio.
Takeuchi N, Ekuni D, Irie K, Furuta M, Tomofuji T, Morita M, Watanabe T. Relationship between periodontal inflammation and fetal growth in pregnant women: a crosssectional study. Arch Gynecol Obstet. 2013 May; 287(5):951-7. doi: 10.1007/s00404-012-2660-4. Epub 2012 Dec 7.
Collins JG, Smith MA, Arnold RR, Offenbacher S. Effects of Escherichia coli and Porphyromonas gingivalis lipopolysaccharide on pregnancy outcome in the golden hamster. Infect Immun. 1994 Oct; 62(10):4652-5.
Offenbacher S, Katz V, Fertik G, Collins J, Boyd D, Maynor G, McKaig R, Beck J. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol. 1996 Oct;67(10 Suppl):1103-13.
Solt I. The human microbiome and the great obstetrical syndromes: a new frontier in maternal-fetal medicine. Best Pract Res Clin Obstet Gynaecol. 2015 Feb; 29(2):165-75. doi: 10.1016/j.bpobgyn.2014.04.024. Epub 2014 Aug 21.
Stadelmann P, Alessandri R, Eick S, Salvi GE, Surbek D, Sculean A. The potential association between gingival crevicular fluid inflammatory mediators and adverse pregnancy outcomes: a systematic review. Clin Oral Investig. 2013 Jul; 17(6):1453-63. doi: 10.1007/s00784-013-0952- 0. Epub 2013 Mar 7.
Han YW. Oral health and adverse pregnancy outcomes-what's next? J Dent Res. 2011 Mar;90(3):289-93. Doi: 10.1177/0022034510381905. Epub 2010 Nov 1.
Ren H, Du M. Role of Maternal Periodontitis in Preterm Birth. Front Immunol. 2017 Feb 13; 8:139. doi: 10.3389/fimmu.2017.00139. eCollection 2017.
Bulut G, Olukman O, Calkavur S. Is there a relationship between maternal periodontitis and pre-term birth? A prospective hospital-based case-control study. Acta Odontol Scand. 2014 Nov; 72(8):866-73. Doi: 10.3109/00016357.2014.919663.
Abati S , Villa A , Cetin I , Dessole S , Lugliè PF , Strohmenger L , Ottolenghi L , Campus GG . Falta de asociación entre el estado periodontal de la madre y los resultados adversos del embarazo: un estudio epidemiológico multicéntrico. J Matern Fetal Neonatal Med. 2013 Mar; 26 (4): 369-72. doi: 10.3109 / 14767058.2012.733776.
Aguilar-Cordero MJ, Rivero-Blanco T, Mur-Villar N, Rodríguez-Blanque R, Moraleda-Hurtado MD, Fernández-Curbero LE, Sánchez-López AM. Conocimiento de la salud bucodental de las mujeres embarazadas. Revisión sistemática. JONNPR. 2018;3(3):202-214. DOI: 10.19230/jonnpr.2137
Reza Karimi M, Hamissi JH, Naeini SR, Karimi M. La relación entre el estado periodontal materno y los recién nacidos prematuros y de bajo peso al nacer en Irán: un estudio de control de casos. Glob J Health Sci. 28 de septiembre de 2015; 8 (5): 184-8. Doi: 10.5539 / gjhs.v8n5p184.
Portal de la junta de Andalucía. Salud bucodental. http://www.juntadeandalucia.es/temas/salud/derechos/bucodental.html
Portal de la junta de Andalucía. Embarazo. http://www.juntadeandalucia.es/temas/salud/servicios/embarazo.html
Embarazo, parto y atención puerperal. Servicio andaluz de salud. http://www.juntadeandalucia.es/servicioandaluzdesalud/principal/docume ntosacc.asp?pagina=gr_cartera_I_2_6_4
Díaz-Quijano D M. Pinzón-Flórez C E. Oliveros-Rodríguez H.Castillo- Zamora M F. Frecuencia de asistencia a la consulta odontológica en el control prenatal y factores asociados en un hospital público de Bogotá, Colombia, 2011-2012. Rev Colomb Obstet Ginecol [Internet]. 2016 Dec [cited 2018 July 08]; 67(4): 288-298. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0034-74342016000400288&lng=en. http://dx.doi.org/10.18597/rcog.1093.
Puertas A, Magan-Fernandez A, Blanc V, Revelles L, O'Valle F, Pozo E, León R, Mesa F. Association of periodontitis with preterm birth and low birth weight: a comprehensive review. J Matern Fetal Neonatal Med. 2018 Mar; 31(5):597-602. doi:10.1080/14767058.2017.1293023. Epub 2017 Feb 28.
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