Afecciones neurodegenerativas: toxicidad por acumulación de metales

Autores/as

  • Iván Antonio García-Montalvo Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. División de Estudios de Posgrado e Investigación. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. Escuela de Medicina y Cirugía. Universidad Anáhuac Oaxaca. Blvd. Guadalupe Hinojosa de Murat No. 1100. C. P. 71248. San Raymundo Jalpan, Oaxaca
  • Cecilia Martínez-Gutiérrez Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca
  • Marco Antonio Sánchez-Medina Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. División de Estudios de Posgrado e Investigación. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca
  • Alma Dolores Pérez-Santiago Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. División de Estudios de Posgrado e Investigación. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca
  • María de Jesús Ramírez- Altamirano Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca

DOI:

https://doi.org/10.19230/jonnpr.2944

Palabras clave:

Enfermedades neurodegenerativas, Neurotoxicidad, Metales

Resumen

Las enfermedades degenerativas del sistema nervioso se manifiestan por diversos síndromes, el síntoma predominante es la demencia progresiva, estas afecciones neurodegenerativas ocasionan  lteraciones en la conciencia o bien en el sistema nervioso conllevando a un daño severo en las células  neuronales, estas patologías son consideradas graduales, progresivas y de etiología variada, tanto genética  como adquirida. En esta revisión, se abordan y describen los riesgos por toxicidad a través de  metales presentes en el día a día de la población, estos metales pueden encontrarse en alimentos, bebidas,  o bien en ambientes  laborales, son capaces de provocar daños neuronales severos además de  inducir una necrosis o apoptosis en todo el sistema nervioso central y periférico, pudiendo desencadenar  una aparición temprana de Enfermedad de Parkinson, Alzheimer, Huntington, Demencia y Esclerosis  Lateral Amiotrófica, predisponiendo así a poblaciones cada vez más jóvenes.

 

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2019-03-21